Chemical Warfare—A Chemical and Toxicological Review
نویسندگان
چکیده
منابع مشابه
Multiple Chemical Sensitivity: Toxicological and Sensitivity Mechanisms
Cases of multiple chemical sensitivity (MCS) are reported to be initiated by seven classes of chemicals. Each of the seven acts along a specific pathway, indirectly producing increases in NMDA activity in the mammalian body. Members of each of these seven classes have their toxicant responses lowered by NMDA antagonists, showing that the NMDA response is important for the toxic actions of these...
متن کاملChemical Similarity and Threshold of Toxicological Concern
There are many national, regional and international programmes – either regulatory or voluntary – toassess the hazards or risks of chemical substances to humans and the environment. The first step inmaking a hazard assessment of a chemical is to ensure that there is adequate information on each of theendpoints. If adequate information is not available then additional data is nee...
متن کاملUsing IUCLID for Worldwide Exchange of Chemical and Toxicological Information
A database management tool (IUCLID) has been created in order to provide with administering chemical and toxicological data sent in structured form due to existing EU legislation. This tool also offers – beyond the normal dataset administration functionality – mechanisms for data fusion, data reproduction and data deployment. Thus IUCLID is used not only by who has to receive submissions of tha...
متن کاملAllergological and Toxicological Aspects in a Multiple Chemical Sensitivity Cohort
BACKGROUND Multiple chemical sensitivity (MCS) is a chronic condition characterized by an exaggerated response to toxicants. We ascertained the prevalence of allergy to metals and toxicological aspects in MCS patients. METHODS We conducted a retrospective review of medical records of 41 patients with MCS. We performed patch testing (n = 21) for dental series and did lymphocyte transformation ...
متن کاملPharmacokinetics, chemical interactions, and toxicological risk assessment in perspective.
Chemical mixtures and multiple routes of exposure are frequently difficult problems for exposure and risk assessors. Chemicals can interact synergistically or antagonistically at a variety of physiologic and biochemical loci within target cells. Many of these interactions can be accounted for with a thorough understanding of the pharmacokinetics of the compounds in the mixture. Many pharmacokin...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: American Journal of Public Health and the Nations Health
سال: 1944
ISSN: 0002-9572
DOI: 10.2105/ajph.34.5.455